The Mouse Estrus Detector by ELMI (MEDPro™) is an innovative tool designed to detect when a female mouse is in the estrus phase, improving the efficiency and accuracy of breeding and research. Here's a brief overview based on your description:
Why the Device is Needed:
- Cycle Identification: Female mice go through different phases in their reproductive cycle, and knowing when they are in the estrus phase is important for breeding, experiments, and minimising the number of animals needed for research.
- Current Challenges: Traditional methods, such as vaginal smear analysis, are time-consuming, invasive, and stressful for the animals.
How the Device Works:
- Tiny Probe: A small, smooth probe is gently inserted into the mouse’s vagina.
- Electric Resistance Measurement: The probe sends a tiny, harmless electric signal to measure tissue resistance, which varies throughout the reproductive cycle.
- Estrus Detection: Tissue resistance is higher during estrus. If resistance exceeds 6 kΩ, the device identifies that the mouse is in the estrus phase.
Advantages:
- Quick & Painless: The process takes seconds, minimizing stress and discomfort for the mouse.
- Accuracy: More reliable and faster than traditional methods like visual checks or lab tests.
Practical Benefits:
- Helps researchers time breeding and experiments more effectively, reducing the number of animals needed.
- Aligns with the 3Rs principle (Replacement, Reduction, and Refinement) in animal research, promoting ethical practices.
In summary, the MEDPro™ is a fast, accurate, and non-invasive tool that enhances animal welfare while improving research outcomes.
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